The purpose of the present study was to investigate the spiritual values and spiritual personality among MBBS and Social Work Muslim students. Therefore, 194 students (86 = MBBS & 108= Social Work) enrolled in Aligarh Muslim University, India were selected using the random sampling technique. To reach the findings of study, Independent Samples T-test were employed using the SPSS software. The empirical results of the current study indicated the significant difference between MBBS and Social Work students on spiritual values and it’s all dimensions viz. altruistic values, humanistic values, personal values, divine values and affective values. MBBS students showed higher mean score on spiritual values and its’ all dimensions as compared to the Social Work students. Further, no significant difference was found between MBBS and Social Work students on spiritual personality and it’s any dimensions viz. noble attitude toward others and moral rectitude. To extend the validity of present findings suggestions for future research proposed.