ARCHIVES
VOL. 8, ISSUE 4 (2023)
Skin grafting: A promising approach for enhancing wound healing and tissue regeneration
Authors
Lucía Villegas-Coronado, Diana Villegas-Coronado
Abstract
Wound healing is a complex biological process that involves
inflammation, cellular proliferation, and extracellular matrix remodeling.
However, the regenerative capacity of skin in adult mammals, including humans,
is limited, often resulting in the formation of scar tissue with cosmetic and
functional implications. Skin grafting, a surgical procedure in which healthy
skin tissue is transplanted onto a damaged or lost skin site, has emerged as an
effective approach in promoting wound healing. This review provides an overview
of skin grafting as a treatment modality for extensive wounds, burns, ulcers,
and surgical sites with skin loss. The procedure involves transplanting skin
from a donor site to the recipient site, providing temporary coverage and
protection while facilitating the integration of the graft with the surrounding
tissues. Skin grafts promote wound healing through various mechanisms,
including the release of growth factors and cytokines, induction of wound
contraction, provision of an extracellular matrix scaffold, and stimulation of
the different stages of wound healing. By supporting natural healing processes,
skin grafts contribute to efficient wound healing and improvement in both the
appearance and function of the healed area. Understanding the role of skin
grafts in wound healing enhances the ability to manage wounds effectively and
minimize patient morbidity.
Download
Pages:17-18
How to cite this article:
Lucía Villegas-Coronado, Diana Villegas-Coronado "Skin grafting: A promising approach for enhancing wound healing and tissue regeneration". International Journal of Academic Research and Development, Vol 8, Issue 4, 2023, Pages 17-18
Download Author Certificate
Please enter the email address corresponding to this article submission to download your certificate.