This present study was done to evaluate the effect of different basal chemical fertilizers singly and in combination at varying application rates on the growth and yield attributes of tomato (Lycopersicon esculentum Mill.). The field experiment was carried out in a randomized complete block design (RCBD) as a 3 x 3 factorial trial treatment with four replicates. Data was collected on number of: leaves, branches, fruits, flowers; plant height and fruit yield. All the collected data were subjected to statistical analysis. The results revealed that there were significant (p< 0.05) differences in number of: leaves, branches, fruits, flowers; plant height and fruit yield. In these parameters, the highest mean values were registered in treatment F3Compound D + Gypsum (combination of chemical fertilizers Compound D + Gypsum) than those in the chemical fertilizers applied alone or control treatment. The highest mean yield was significant from treatment A1300kgs with the highest application rate. The result determined that application of chemical fertilizers F3Compound D + Gypsum x A1300kgs can increase the growth and total yield in tomato cultivation over the standard control.