Events over the years have shown that the status and perception of teachers by the society and the teaching profession in Nigeria and many other countries of the world have nosedived. An assessment of the student’s perception towards the teaching profession was carried out. A self-structured questionnaire named Students’ Perception of Teaching Profession Questionnaire (SPTPQ) was interviewer-administered to 250 senior secondary school, students in Port Harcourt. The study showed that the students agreed that becoming a teacher may be attractive and be appropriate for them (Likert mean ≥ 2.5). However, they disagreed that the teaching profession suits their lifestyle and personality (Likert mean < 2.5). Based on the results of the study, the students indicated that their parents think teaching is a noble profession. However, they rejected the statement that their parents think the teaching profession is suitable for them. The data showed that 52 (38.81%) of the male students agreed that the idea of becoming a teacher attracts them and 82 (61.19%) disagreed. Among the female students, 60 (51.72%) agreed that the idea of becoming a teacher attracts them, while 56 (48.28%) disagrees. The null hypothesis “There is no significant difference in the perception of male and female students towards the teaching profession” was rejected (Chi-square = 4.19, p =0.0405). The null hypothesis “There is no significant difference in the perception of art and science students towards the teaching profession.” was not rejected (Chi-square = 1.13, p-value =0.2877). The study showed that parental influence and gender are significant influences in the perception of choosing teaching as a profession.