This study aimed to study impact of economic variables on unemployment rate such as( GDP, INF, G, EX, POP ) all this variables is represent independent variables) according to this we enable to determine which the variables impacted on the unemployment rate, and what the nature of relationship between the unemployment rate and (GDP, INF, G, EX, POP) The study hypothesized that the most important variables effect on unemployment rate in Sudan (GDP, INF, G, EX, POP) and assumed that there is positive statistically significant relationship between size of population and unemployment rate, and also assumed that there is negative statistically significant relationship between (gross domestic product and inflation and government expenditure exchange rate unemployment rate). We found that the size of population is impacted in the unemployment rate.