This study examines the effect of Entrepreneurs in Agriculture Value Chain optimization in Nigeria. The importance of this study is rooted in the fact that Nigeria is a major producer of agricultural product, yet the country has not received very commensurate income from agriculture due to the fact that most of the products are exported over-sea in their raw form, a situation that has led to Nigeria depending on developed countries for the finished products of its original agriculture products such as chocolate, candies etc. A survey design is adopted for the study by designing and administering questionnaire to the target population of the study. ANOVA test is used in analyzing the data collected and it was discovered that there is no significant difference between the effects of different types of entrepreneurs in Nigeria agriculture value chain maximization. It is recommended that different entrepreneurs operating in agriculture value chain should be encouraged equally through the provision of investment incentives such as low interest loans, subsidies on agriculture equipment, favorable business environment etc.