Background: Previous trials have investigated the Effect of dual task training in diagnosed patients with Diabetic Neuropathy. No clinical trial examining the effect of this type of training under fixed and variable priority instructions set in diabetic neuropathic patients with mobility impairment has been reported in the literature. Objectives : To evaluate the Effect of dual task training under fixed and variable priority instructions set in diagnosed patients of Diabetic Neuropathy with mobility impairment. Method: 30 diagnosed patients of Diabetic Neuropathy with balance impairment were assigned in to 2 groups. The group A received Dual Task Training with fixed priority Instruction set while group B received Dual Task Training with Variable priority Instruction set. Both groups received the selected treatment over a 4 week periods. Outcome measures were evaluated at baseline, 2nd week and 4th week. Results: The study shows significant improvement in locomotor ability in Diabetic Neuropathy with dual task training under fixed and variable priority instruction set. But improvement is more marked under variable priority instruction set. Conclusion: The research hypothesis which states that there will be more improvement in locomotor ability trained with variable priority instruction set than fixed priority in diabetic neuropathy with mobility impairment has been accepted.