Performance enhancing drugs have a lot of side-effects on the human body. In some cases, it leads to the death if it is taken in excessive quantity. It is noticed that most of the wrestlers take steroid to gain the weight quickly. Their weight is increased but is found that if they stop taking steroid then their weight goes decreased and a lot of side-effects such as skin problem, stomach problem have evolved. The mostly used performance enhancing drugs are promyogenic drugs which are used to increase the muscle or decrease the fat of the body. These are pharmacologic agents which are normally used by the athletes or non-athletes weightlifters to gain weight. The current article highlights the adverse effects of taking performance enhancing drugs in excessive quantity.