Aim: To evaluate the effects of an ergonomic intervention in musculoskeletal disorders in computer users. Objective: To determine the effectiveness ofan ergonomic intervention on pain and disability among computer users Materials: Inch tape Goniometer. Methodology: 40 Patients with musculoskeletal disorders were selected based on the inclusion and exclusion criteria and subjects were then allocated into two groups group A and group B. Group A (n=20) will receive ergonomic advices and relaxation exercise Group B (n=20) will be advised to take hot packs for 15 to 20 minutes. Outcome Measures: Cornell musculoskeletal discomfort questionnaire, Numerical Pain Rating Scale. Statistical Analysis: The collected data was tabulated and analyzed using inferential statistics to assess all the parameters mean and standard deviation was used. To find out significant changes within the group of pre and post-test by unpaired t-test was used. Results: Statistical Analysis of post-test, Cornell Musculoskeletal Discomfort Questionnaire (CMDQ) and Numerical Pain Rating Scale (NPRS) revealed that there is highly statistically significant difference seen in group A than group B. Conclusion: This study concluded that ergonomic intervention can be incorporated for pain and disability which is more effective.