The study was conduted from March to May in the year 2017 and coverd Tuticorin and Tirunelveli district fish farms. In the present study gold fish, koicarp, guppy, oscar, flowerhorn, mollies, cichlids were screened for the pathological infections. From the result clearly showed, No specific species and location specific diseases were identified. Since all varieties of fishes both infected and uninfected are distributed at different stages of marketing to all parts of Tamil Nadu and leading to spread of infectious diseases.