Patients with chronic illness require great social support and efficient caregivers. They tend to develop psychological distress, anxiety issues, stress and eventually their quality of life and satisfaction with life deteriorates. Hope is a positive factor which helps patients with chronic illness to fight with such adversity and stressors. The current investigation was designed to study the interrelationship between perceived social support, life satisfaction and hope among chronically ill patients. The sample for the current investigation consisted of 50 chronically ill patients (where 25 are male patients and 25 are female patients) in the age group of 35-45 years in the tricity of Panchkula, Mohali and Chandigarh. For this purpose, Multidimensional Scale of Perceived Social Support (Zimet et al., 1988), Satisfaction with Life Scale (Diener et al., 1985) and Adult Hope Scale (Snyder et al., 1991) were administered to the sample. Inter- correlational analysis was used for statistical analysis. Results were discussed in terms of its implications.