Infertility has been a major medical and social paradigm since the dawn of human existence and women have always been the symbol of fertility. 10-15% of marriages prove to be childless, female factor are responsible for 40% of infertility cases in which anovulation accounts for 30%. The serious consequences of chronic anovulation are infertility and a greater risk for development of endometrial cancer. In the entire infertility factor, disorder of ovulation has the widest range of treatment armamentarium with the administration of ovulation inducing agents to achieve pregnancy rates without increase in untoward side effects. It has been mentioned in Unani encyclopedias that the cause of female infertility is decrease in the quantity of mani (ovum) i.e. oligo ovulation or anovulation; more over, the defect in ovum is attributed to sue mizaj barid which solidifies ovum leading to anovulatory infertility. Unani physicians recommended various formulations for the treatment of anovulatory infertility possessing the properties like muqawwi rehm (uterine tonics), moaene hamal (helpful in conception) and mawallide mani (ovulation inducing) which has to be used from 5^th day of menstrual cycle (corresponds to ovulation inducing drugs). This shows that the concept of ovulation induction was well known to Unani physicians. These drugs are known to contain phytohormones and may induce ovulation by maintaining hormonal balance. The aim of this paper is to review the etiopathogenesis, diagnostic and curative aspect present in Unani literature with simultaneous correlation with modern literature and to develop evidence based approach through research in Unani medicine in the management of Anovulatory infertility.