Medicinal plants have played an important role in treating and preventing a verity of diseases throughout the world. Bangladesh still depends on medicinal plants and most of them have general medicinal plants which are used for treating a verity of ailments. Cuscuta reflexa belongs to the family of Convolvulaceae. The aim of the resent study was to evaluate a comprehensive review on the phytochemical and pharmacological aspects of Cuscuta reflexa. It has been investigated for hepatoprotective, antimicrobial, antitumor, wound healing, hypoglycemic, anti-HIV, diuretic, anticonvulsant, anti-inflammatory and anticancer activities. Many chemical constituents have been isolated from Cuscuta reflexa such as cuscutin, cuscutamine, kaempferol, quercetin, myricetin, amarbelin, β-sitosterol, ararbelin, luteolin, dulcitrol, cafferi acid.